Preliminary evaluation of the genotoxic potential of a. Cytotoxic and genotoxic effects of perfluorododecanoic. Recent studies have suggested that oxidative stress and dna damage may play a role in the pathophysiology of bipolar disorder bd. Levaluation du risque genotoxique a ete realisee par le test des micronoyaux. Effects of mood stabilizers on dna damage in an animal model. Cardiovasculaire hypotension le traitement par bortezomib pour injection est frequemment associe a une hypotension. Test concentrations were based on the level of toxicity in a preliminary toxicity test with strain ta100 both without and with s9mix. As per the law relating to information storage and personal integrity, you have the right to oppose art 26 of that law, access art 34 of that law and rectify art 36 of that law your personal data. The full text of this article is available in pdf format. None of the assays was the most sensitive for every substance analyzed. Test comet test du micronoyau dommages a ladn pfdoa medaka 1 introduction the aquatic ecosystem is the. Non carcinogene en cas dexposition a long terme souris, dermique. Test daberration chromosomique in vitro, avec ou sans activation metabolique, resultat.
Cytotoxic and genotoxic effects of perfluorododecanoic acid. Pharmacology, pharmacologie, genotoxicologie, micronoyau, kinetochore, clastogene, aneugene, immunomarquage, 06o pharmacology, pharmacy, pharmaceutical. Com is registrered at the cnil, declaration n 1286925. Effects of mood stabilizers on dna damage in an animal. Populations particulieres femmes enceinteseffets teratogenes. We investigated the effects of the mood stabilizers lithium and valproate on amphetamineinduced dna damage in an animal model of mania and their correlation with oxidative stress markers. Evaluer en temps reel et in vitro le potentiel cancerogene. Virtualization is the isolation of one computing resource from the others virtualization results in more efficient resource utilization, and enables greater flexibility and simplified change management. Peut provoquer des anomalies genetiques generated by iuclid 6 v3. Sommaire i presentation du thalidomide ii pharmacologie. Essai du micronoyau souris male et femelle resultat. Pdf cytotoxic and genotoxic effects of perfluorododecanoic. Test du micronoyau invivo sourishamster nonguideline.
Utilisation du marquage des kinetochores dans le test du. Ocde ligne directrice 406 mutagenicite sur les cellules germinales test du micronoyau lymphocyte resultat. Nom du produit super one second name of same product ufi and other identifiers clp unique formula identifier ufi. Comparaison des resultats du test des cometes et du test des micronoyaux dans des etudes dexposition professionnelle faisant appel a ces 2.
Liver s9 fraction from aroclor 1254induced rats was used as exogenous metabolic activation system. This study compared the genotoxic potential of a polymeric associative thickener used in topically applied emulsions preserved with three different preservative systems. Evaluer en temps reel et in vitro le potentiel cancerogene des. The method used for the assessment of genotoxicity is the in vitro micronucleus test organization for economic cooperation and development oecd guideline number 487.